Genomic and Molecular Approaches in Medical Sciences

  • Dhavendra Kumar Himalayan Institute of Medical Sciences, Swami Rama Himalayan University
  • Vinit Mehrotra


An important milestone in the history of medical sciences is the recent completion of the human genome
sequence. The progress on identification of approximately 23,000 genes and their regulatory regions provides the
framework for understanding the molecular basis of disease. This advance has also laid the foundation for a broad
range of genomic tools that can be applied to medical sciences. These developments in gene and gene product
analysis across the whole genome have opened the way for targeted molecular genetic testing in a number of
medical disorders. This is destined to change the practice of medicine: which will be more focused on
individualized, referred to as 'personalized medicine'. However, despite these exciting advances, many practicing
clinicians perceive the role of molecular genetics, in particular that of medical genomics, as confined to the
research arena with limited clinical applications. Genomics-based advances are increasingly applied in disease
susceptibility screening, accurate clinical diagnosis, assessing the prognostication, personalized therapeutics,
and prediction of treatment outcomes in various areas of clinical medicine. The genomic and molecular
developments are promising to make the future clinical medicine practice to be personalized, premptive,
predictive, participatory and preventive.

Apr 23, 2019
How to Cite
KUMAR, Dhavendra; MEHROTRA, Vinit. Genomic and Molecular Approaches in Medical Sciences. SRHU MEDICAL JOURNAL, [S.l.], v. 1, n. 3, p. 99 - 106, apr. 2019. ISSN 2456-7825. Available at: <>. Date accessed: 13 aug. 2020.
Review Article